糖心视频

Dr. Noriko Daneshtalab

Associate Dean, Graduate Studies and Research
Associate Professor
Cross appointed, Faculty of Medicine

Dr. Daneshtalab graduated from University of Alberta with her B.Sc. (Pharmacology; 1998) and PhD (Pharmaceutical Sciences; 2005). She completed two post-doctorates, first in John P. Robarts institute for research in London, Ontario (2004-2006; Cell Biology) and second in 糖心视频 University of Newfoundland (2007-2010; Cardiovascular). Her work helped characterize aspects of GPCR signaling, membrane trafficking, and protein-receptor interaction (London), and the multi-factorial mechanisms involved in hemorrhagic stroke development in stroke-prone animal models (Newfoundland).

Research areas of interest:

  • Mechanisms of cerebrovascular dysfunction associated with chronic inflammation (particularly autoimmune disease) leading to stroke development
  • The PK/PD alterations of both cardiovascular and immuno-modulatory drugs with stroke development in the presence and absence of arthritis models
  • Role of the pro-inflammatory mediator in promoting therapeutic failure of cardiovascular disease
  • The role of disease severity and antihypertensive drug therapy on cardiovascular outcomes in RA patients

Teaching areas of interest: Pharmacokinetics and Pharmacodynamics, General pharmacology

Current projects:

  • Development of a hypertensive-arthritic animal model
  • Mechanisms of cerebrovascular dysfunction associated with chronic inflammation (particularly autoimmune disease) leading to stroke development
  • Molecular signaling associated with cerebrovascular dysfunction leading to loss of function
  • Role of IL-17a in cerebrovascular dysfunction

Selected award:

Ignite Research Development Corporation (RDC) Fund

Selected publications:

Shaker MA, Daneshtalab N, Dor茅 JJE, Younes HM.. (2012). . Journal of Bioactive and Compatible Polymers. 27: 78-94.

Smeda JS, Daneshtalab N.. (2011). . Journal of Cerebral Blood Flow and Metabolism. 31(2): 476-85.

Daneshtalab N, Smeda JS. (2010). . Cardiovascular Research. 86(1): 160-8

Contact:

Dr. Noriko Daneshtalab
Tel: 709-864-2683